Structural Heart · Medical Devices

Structural heart, for more patients.

Septablate is developing a new therapy to open structural heart treatment to patients whose anatomy currently excludes them.

Minneapolis, MN
01 / Problem

Breakthrough therapies. A population still excluded by anatomy.

The last decade transformed treatment of structural heart disease. Catheter-based valve therapies that once required open-chest surgery are now delivered through the femoral vein, in cases that previously had no option at all.

But a meaningful share of patients screened for these therapies never reach the procedure. Their underlying anatomy disqualifies them on the imaging table. They are sent home on medical management, with limited alternatives and a disease that often gets worse on its own.

02 / Team

The founding team.

Co-founder & CEO

Peter DeLange

25+ years · Cardiovascular medtech

Medtech executive, founder, and former CEO with two and a half decades of experience leading Class II and Class III cardiovascular device programs through development, regulatory execution, capital formation, and strategic exit.

Founded a contract development firm later acquired by a public medtech acquirer. Prior senior leadership roles include implantable Class III commercial programs and interventional cardiology catheter platforms.

Co-founder & CTO

Thomas McPeak, PE

35+ years · Catheter R&D · Inventor

Licensed Professional Engineer with deep experience in catheter-based interventional systems, tissue and lesion modeling, and preclinical animal model development. Named inventor on the underlying technology.

More than a decade as Senior Principal R&D Engineer in a top-tier medtech advanced development group, with earlier leadership roles in endovascular catheter and atherectomy programs.

Get in touch

A small team in Minneapolis. Reach out.

Septablate is small, early, and focused on the work. We always read direct notes. If you're a clinician, collaborator, vendor, or investor and you'd like to start a conversation, please be in touch.